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. Author manuscript; available in PMC: 2011 Dec 8.
Published in final edited form as: Fam Cancer. 2010 Dec;9(4):625–633. doi: 10.1007/s10689-010-9356-3

Table 4.

Associations of 9p21 SNPs with tanning ability in 53 melanoma families1.


SNP		 Tan/Little
burn
 Burn/Little
tan
 Model12
 Model23
N % N % OR 95% CI P OR 95% CI P
    IFNW1
rs10964862
  TT 100 38.5 118 50.4  Ref  Ref
  TG 129 49.6 97 41.5 0.59 0.38 0.92 0.02 0.60 0.38 0.94 0.03
  GG 31 11.9 19 8.1 0.35 0.16 0.78 0.01 0.32 0.14 0.74 0.007
 P trend 0.003 0.002
TUSC1
rs13290968
  GG 180 78.6 133 64.3 Ref Ref
  GC+CC   49 21.4   74 35.7   2.31 1.38 3.89 0.002  2.25 1.31 3.84 0.003
 P trend 0.0006 0.002
1.

ORs and P values are obtained from likelihood ratio test in conditional logistic regression with tanning ability (comparing burn/little tan to tan/little burn) as the outcome variable.

2.

Model 1: age, gender, CMM, and CDKN2A adjustment.

3.

Model 2: age, gender, CDKN2A, CMM, number of nevi, solar injury, and MC1R adjustment.