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Effect of SCH-58261(SCH; 1 μM) on the NECA-induced increase in CF (A), HR (B), and LVDP (C) in WT (n = 6) and A2BKO (n = 4) mice. Values are means ± SE. *Significant difference between drug-induced effects in the presence of antagonist compared with their corresponding control; #Significant difference in baselines in the presence of antagonist compared with their corresponding control; $significant difference between WT and A2BKO antagonist-treated groups (P < 0.05).
