Fig. 2.
Evidence that C-PAF stimulates sodium-hydrogen exchanger (NHE1). A: example pHi signals from 3 different myocytes showing the response of pHi to 200 nM C-PAF under control conditions and in the presence of zero [Na+]o and 60 μM cariporide, both of which block the C-PAF-induced rise in pHi. B: summarized results of ΔpHi induced by 10 min superfusion with 200 nM C-PAF under control conditions (n = 16), zero [Na+]o (n = 4), and 60 μM cariporide (n = 4). **P < 0.01, unpaired control vs. NHE1 blockade.