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RSG attenuates HYP-induced increases in HIF-1α and NF-κB mRNA levels in mouse lung and in HPAEC. C57BL/6 mice (A and B) or HPAEC (C and D) were exposed to NOR or HYP ± RSG as described in Fig. 1. Each bar represents the mean ± SE HIF-1α or NF-κB mRNA level relative to ribosomal 9S and expressed relative to control. P < 0.05 vs. NOR (*) and 9s. HYP (+); n = 5–9.
