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. 2011 Sep 9;301(6):L927–L936. doi: 10.1152/ajplung.00049.2011

Fig. 1.

Fig. 1.

Eosinophils are necessary for pulmonary vascular remodeling in adiponectin-deficient (APN−/−) mice. A and B: percentage and number of mononuclear cells (Mono), neutrophils (PMN), and eosinophils (Eos) in the bronchoalveolar lavage (BAL) from APN−/− mice following ovalbumin (OVA) immunization and challenge and pretreatment with anti-interleukin (IL)-5 or isotype control antibodies (n = 6–7 mice/group). C: representative hematoxylin- and eosin-stained lung sections of APN−/− mice following OVA immunization and challenge and treatment with isotype control (i) or anti-IL-5 (ii) antibodies (Ab) (×100 magnification). Pulmonary arteries are indicated with black arrows. Black bars are 100 μm (representative images from n = 6–7 mice/group). D: vessel wall thickness (% of total) in small and medium preacinar blood vessels in lung sections from APN−/− mice following OVA immunization and challenge and treatment with isotype or anti-IL-5 control antibodies (n = 6–7 mice/ group). E: right ventricular systolic pressure (RVSP) measured in APN−/− mice following OVA immunization and challenge and treatment with isotype or anti-IL-5 control antibodies (n = 5 mice/group).