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. 2011 Sep 21;301(6):R1723–R1730. doi: 10.1152/ajpregu.00382.2011

Fig. 7.

Fig. 7.

A: quantitation of EETs in the perfusate collected from shear stress-stimulated (2 and 10 dyn/cm2) mesenteric arteries of l-NAME-treated female rats in control conditions (N/n = 6/12) and after transfected with CYP2C7 short interfering RNA (siRNA; N/n = 5/15) or nonsilencing siRNA (N/n = 5/12) for 72 h, respectively. B: flow-induced dilation in control conditions (N/n = 5/10) (day 0) and after incubation with CYP2C7 siRNA (N/n = 5/8) or nonsilencing siRNA (N/n = 5/5) for 72 h (day 3). %PD, percent passive diameter. C and D: endothelial CYP2C7 and 2C11 mRNA (C) and CYP2C7 protein (D) expressions in mesenteric arteries in control conditions and transfected with CYP2C7 siRNA or nonsilencing siRNA for 24–72 h. Values are means ± SE. *Significant difference from controls and nonsilencing siRNA, P < 0.05.