Table 1.

Subject characteristics, lipids, and postheparin lipase activity - baseline values and responses to aerobic exercise training

	Baseline Values				Response to Exercise Training
		LIPC genotype				LIPC genotype
Characteristic	Overall* (n = 76)	CC (n = 51)	CT (n = 25)	P	Overall* (n = 76)	CC (n = 51)	CT (n = 25)	P
Age, yr	58.0 ± 0.7	58.3 ± 0.9	57.5 ± 1.1
Women/Men	42/34	27/24	15/10
Females HRT, %	52	52	53
Weight, kg	83 ± 1.4	82 ± 1.6	86 ± 2.4		−1.2 ± 0.3%§	−1.0 ± 0.4%*	−1.8 ± 0.5%‡
BMI, kg/m2	28.3 ± 0.4	28.0 ± 0.5	28.8 ± 0.9		−1.3 ± 0.3%§	−1.0 ± 0.4%*	−1.9 ± 0.5%§
Body fat, %	36 ± 0.7	36 ± 0.9	38 ± 1.1		−1.5 ± 0.24§	−1.5 ± 0.29§	−1.5 ± 0.43‡
Visceral fat, cm2	132 ± 4	129 ± 5	138 ± 8		−7 ± 1.8%§	−7 ± 2.2%‡	−8 ± 3.3%*
V̇o2max, ml · kg−1 · min−1	25.5 ± 0.4	26.1 ± 0.5	24.2 ± 0.7	0.02
V̇o2max, l/min	2.10 ± 0.03	2.13 ± 0.04	2.03 ± 0.07		15.0 ± 0.4%§	14.9 ± 0.5%§	15.8 ± 0.6%§
Total cholesterol, mg/dl	211 ± 3	206 ± 4	220 ± 5	0.05	−1 ± 1.1%	0 ± 1.4%	−2 ± 1.5%
Triglycerides, mg/dl	152 ± 7	149 ± 9	156 ± 13		−6 ± 3%*	−7 ± 3%*	−2 ± 6%
HDL-C, mg/dl	44 ± 1.2	43 ± 1.4	48 ± 2.0	0.03	6 ± 1.1%§	7 ± 1.4%§	4 ± 1.8%*	0.03
HDL2-C, mg/dl	2.9 ± 0.5	2.2 ± 0.5	4.5 ± 1.0	0.05	0.9 ± 0.3†	0.6 ± 0.3	1.5 ± 0.8
HDL3-C, mg/dl	42 ± 0.9	41 ± 1.2	43 ± 1.4		5 ± 1.1%§	6 ± 1.3%§	2 ± 1.9%	0.03
LDL-C, mg/dl	134 ± 3	131 ± 4	140 ± 5		−1 ± 1.5%	1 ± 2.0%	−5 ± 2.1%*
HL activity, nmol · min−1 · ml−1	248 ± 10	260 ± 13	223 ± 14	(0.07)	−4 ± 6	7 ± 7	−24 ± 8†	0.01
LPL activity, nmol · min−1 · ml−1	189 ± 7	185 ± 7	197 ± 14		14 ± 7*	23 ± 8†	−6 ± 11	0.05

Values are means ± SE and are adjusted by age, sex, and hormone replacement therapy (HRT). SI unit conversion factors: To convert Triglycerides from mg/dL to mmol/l multiply by 0.0113. BMI, body mass index; HDL and LDL, high- and low-density lipoproteins, respectively. To convert cholesterol from mg/dL to mmol/l, multiply by 0.026.

^*P ≤ 0.05,

^†P ≤ 0.01,

^‡P ≤ 0.005,

^§≤ 0.001 for within-group responses to exercise training.