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. 2011 Aug 11;111(6):1877–1887. doi: 10.1152/japplphysiol.00313.2011

Table 1.

Effect of MCAO durations on ischemic brain injury

Group Neurological Deficit Infarct Volume Death Rate
MCAO-30min 1.0 ± 0.5 (0∼2) (n = 12) 9.5%±2.2% (n = 12) 0 (0 out of 12)
MCAO-45min 4.0 ± 1.0 (3∼5) (n = 30)Δ 22.6%±2.7% (n = 12) 0 (0 out of 30)
MCAO-60min 6.0 ± 1.0 (5∼7) (n = 25)Δ 33.4%±3.1% (n = 12) 16.7% (5 out of 30)

ΔP < 0.01 vs. middle cerebral artery occlusion (MCAO)-30 min (rank-sum test). ☆P < .0.01 vs. MCAO-30min (t-test). ▾P < .0.01 vs. MCAO-30 min (χ2 test). Note that the death rate, neurological deficit, and infarct volume increased with the duration of MCAO.