Figure 3.

dyb-1 mutant suppressed locomotion and egg-laying phenotypes of slo-1(gf) and phenocopied slo-1(lf) in head-bending behavior. A, B, dyb-1 mutant suppressed the locomotion (A) and egg-laying (B) defects caused by slo-1(gf), which could be reversed by expressing wild-type DYB-1 in either neurons (Prab-3) or body-wall muscle cells (Pmyo-3). Twenty to 30 worms per group in A and 10 worms per group in B. C, D, Comparisons of full-amplitude head-bending angle and root mean square (RMS) head-bending angle. The head-bending angle was similarly increased in dyb-1 mutant, slo-1(lf), and the double mutant. This phenotype of dyb-1 mutant could be rescued by expressing wild-type DYB-1 in muscle but not neurons. Ten worms per group. *p < 0.01, significantly different between the indicated groups (A, B) or from wild type (C, D) (one-way ANOVA with Bonferroni's post hoc tests).