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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: J Am Geriatr Soc. 2011 Nov;59(Suppl 2):S282–S288. doi: 10.1111/j.1532-5415.2011.03691.x

Table 3A.

Effect of Donepezil on Delirium Presence over time based on the CAM*

Donepezil (n = 7) Placebo (n = 9) p value†
Pre-randomization 1/7 (14%) 4/9 (44%) --
Hospital Interviews (more than one per subject) 7/11 (64%) 9/14 (64%) 0.9
Week 2 3/7 (43%) 3/7 (43%) 1.0
Week 4 1/6 (17%) 3/7 (43%) 0.6
Week 6 3/6 (50%) 3/6 (50%) 1.0
*

Confusion Assessment Method (CAM) - Measure of the presence or absence of delirium. Requires: 1) Acute change with fluctuating course, 2) inattention, and either 3) disorganized thinking or 4) altered level of consciousness

†

P value derived from the Fisher's Exact Test

Overall effect of donepezil on delirium presence over time using a repeated measures logistic regression model from Generalized Estimating Equations: Odds ratio=0.9, 95% Confidence Intervals: [0.4, 2.3].