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. 2011 Sep 14;106(6):3073–3081. doi: 10.1152/jn.00046.2011

Fig. 2.

Fig. 2.

Endocannabinoid signaling is involved in GND-induced suppression of GABAergic transmission. A: representative recording of GABAergic PSCs from a GnRH neuron treated with SR141716 (SR) during the 10 s before and after GND. B: comparison of pre- and post-GND GABAergic PSC frequency in the presence and absence of cannabinoid receptor type 1 (CB1R) antagonist SR (n = 7 cells). C: comparison via t-test of pre- and post-GND GABAergic PSC frequency in the presence of 10 μM orlistat (Orl; an inhibitor of endocannabinoid synthesis) in the recording pipette (n = 9 cells). *P < 0.05 vs. pre-GND values for that same condition. See Fig. 1 for details on box and whisker plots. con, Control.