Table 4.
INaT current properties in substantia nigra pars reticulata GABA and nigral DA neurons at 25°C, filtered at 30 kHz, and sampled at 200 kHz
| Parameter | GABA Neurons | DA Neurons | Significance P |
|---|---|---|---|
| Activation midpoint, mV | −34.81 ± 1.2 (n = 9) | −29.90 ± 1.30 (n = 11) | <0.05 |
| Slope factor k | 7.04 ± 0.17 (n = 9) | 7.75 ± 0.13 (n = 11) | <0.05 |
| 10-90% Rise time (at 0 mV), ms | 0.10 ± 0.004 (n = 9) | 0.11 ± 0.004 (n = 11) | >0.05 |
| 90-10% Decay time (at 0 mV), ms | 0.72 ± 0.03 (n = 9) | 0.68 ± 0.04 (n = 11) | >0.05 |
| Deactivation τ (at −40 mV), ms | 0.16 ± 0.01 (n = 4) | 0.25 ± 0.02 (n = 5) | <0.05 |
Values are means ± SE; n, no. of neurons.