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. 2011 Oct 17;3(5):e00070. doi: 10.1042/AN20110015

Figure 2. Increased TTR mRNA levels in DGCs of HuD-Tg mice.

Figure 2

(A) TTR FISH images from WT and HuD-Tg mice. Low magnification taken using a ×4 objective show expression of TTR mRNA in CP in WT and HuD-Tg mice and in the dentate gyrus of HuD-Tg mice. Scale bar = 750 μm. High magnification (×20) images show increase TTR mRNA in DGC of HuD Tg mice. Scale bar = 150 μm. (B) Quantification of TTR mRNA levels in DGCs of WT and HuD-Tg by ISH and qRT–PCR was performed as described in the Materials and methods section. *P<0.05 and ***P<0.001.