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. Author manuscript; available in PMC: 2012 Sep 6.
Published in final edited form as: Biochemistry. 2011 Aug 9;50(35):7568–7578. doi: 10.1021/bi2004872

Table 1.

KI values of N-alkylamine for the pure sigma-1 receptor.

Compounds KI (μM) pure sigma-1 receptor
Butylamine 477 ± 67
Amylamine 167 ± 35
Heptylamine 21 ± 9
Octylamine 6 ± 3
Dodecylamine 0.2 ± 0.02*
Tretradecylamine 1.0 ± 0.03
Hexadecylamine 3.0 ± 0.36
Octadecylamine 8.5 ± 5.5*
*

Values obtained from Ramachandran et al. (2010) Eur J Pharmacol 609, 19–26.