Table 1.

Group classifications for gene expression analyses.

Gene Expression Analysis
CDR Groups	Dementia Severity	Number of individuals
		Hippocampus	Area 20
0	No dementia	18	18
0.5	Questionable dementia	13	13
1	Mild dementia	9	8
2	Moderate dementia	9	13
3	Severe dementia	12	18
4–5	Very severe/terminal dementia	12	18
Braak Groups	Braak stages
0	None	7	9
I	Mild transentorhinal	8	9
II	Severe transentorhinal	15	16
III	Limbic	10	12
IV	Limbic/Hippocampal CA1	8	8
V	Isocortical	12	15
VI	Isocortical/Primary sensory areas	13	19
NP Density Groups	Plaques (number/mm2)
0	0	24	26
1	1–5	10	13
2	6–10	20	23
3	11–20	14*	14
4	21 and more	5*	12

^*NP density groups 4 and 5 were pooled for gene expression analyses in hippocampus.