Table 3. Carrier frequency and risk reduction by ethnicity.

Ethnicity	Detection rate (%)	a priori riska (95% CI)	Reduced risk for 2-copy result	Reduced risk for ≥3-copy result
Pan-ethnic	91.2	1:54 (1:51–1:57)	1:527	1:5400
Caucasian	94.8	1:47 (1:43–1:51)	1:834	1:5600
Ashkenazi Jewish	90.5	1:67 (1:54–1:83)	1:611	1:5400
Asian	93.3	1:59 (1:47–1:74)	1:806	1:5600
Hispanic	90.0	1:68 (1:57–1:83)	1:579	1:5400
Asian Indian	90.2	1:52 (1:33–1:82)	1:443	1:5400
African American	70.5	1:72 (1:54–1:94)	1:130	1:4200
Not provided	91.3	1:54 (1:48–1:161)	1:536	1:5450

^aa priori risk includes the [1+0], [1+1^d], [2+0] and [2+1^d] allele pairings for individuals with no family history of spinal muscular atrophy.