Table 2. Significantly associated SNPs within ACCN1 analysed in the extended Faroese (FO) and Danish (DK) case–control samples and in the combined sample between Faroese and Danish cases versus Faroese and Danish controls (FO+DK) (stage 3).
| FO | DK | FO+DK | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SNP | Cases | Controls | Ptrend | Cases | Controls | Ptrend | Cases | Controls | P |
| RS8066566 | |||||||||
| A | 16 (0.28) | 41 (0.14) | 0.016 | 62 (0.13) | 192 (0.15) | 0.245 | 78 (0.15) | 233 (0.15) | 0.805 |
| G | 42 (0.72) | 245 (0.86) | 414 (0.87) | 1066 (0.85) | 456 (0.85) | 1311 (0.85) | |||
| RS16589 | |||||||||
| A | 10 (0.17) | 93 (0.32) | 0.020 | 164 (0.34) | 434 (0.34) | 0.895 | 174 (0.32) | 527 (0.34) | 0.392 |
| G | 48 (0.83) | 195 (0.68) | 316 (0.66) | 824 (0.66) | 364 (0.68) | 1019 (0.66) | |||
| RS16585 | |||||||||
| G | 2 (0.03) | 45 (0.16) | 0.016 | 47 (0.10) | 145 (0.12) | 0.297 | 49 (0.09) | 190 (0.12) | 0.072 |
| A | 56 (0.97) | 245 (0.84) | 433 (0.90) | 1115 (0.88) | 489 (0.91) | 1360 (0.88) | |||
| RS12451625 | |||||||||
| A | 1 (0.02) | 28 (0.10) | 0.044 | 37 (0.08) | 102 (0.08) | 0.784 | 38 (0.07) | 130 (0.08) | 0.354 |
| G | 57 (0.98) | 262 (0.90) | 443 (0.92) | 1158 (0.92) | 500 (0.93) | 1420 (0.92) | |||
| RS4289044 | |||||||||
| G | 17 (0.29) | 47 (0.16) | 0.026 | 116 (0.24) | 278 (0.22) | 0.346 | 133 (0.25) | 325 (0.21) | 0.094 |
| C | 41 (0.71) | 243 (0.84) | 362 (0.76) | 980 (0.78) | 403 (0.75) | 1223 (0.79) | |||
| RS8070997 | |||||||||
| G | 7 (0.12) | 12 (0.04) | 0.018 | 78 (0.16) | 175 (0.14) | 0.229 | 85 (0.16) | 187 (0.12) | 0.069 |
| A | 51 (0.88) | 278 (0.96) | 402 (0.84) | 1085 (0.86) | 453 (0.84) | 1363 (0.88) | |||
| RS9915774 | |||||||||
| A | 5 (0.09) | 53 (0.19) | 0.072 | 58 (0.12) | 204 (0.16) | 0.033 | 63 (0.12) | 257 (0.17) | 0.006 |
| G | 53 (0.91) | 233 (0.81) | 422 (0.88) | 1054 (0.84) | 475 (0.88) | 1287 (0.83) | |||
The allele counts are given in numbers and the frequencies are shown in brackets.