Figure 3.

Multiple comparisons of the somatic mosaicism indices harboring 20–79 CAG repeats in the ataxin-2 gene. (a) One-way ANOVA comparison for somatic mosaicism in a cohort of 551 un/expanded alleles. Each range showed differences either in the somatic mosaicism indices or in peak number. (b) Post hoc Newman–Keuls multiple comparisons of the mosaicism indices in the studied sample. Only alleles sized between 27–31 and 32–34 CAG were not different after corrections. Data are presented as mean and standard error of mean (SEM). (c) Somatic mosaicism of unexpanded and expanded pathological (causing SCA2) ATXN2 alleles; arrowheads point to the somatic mosaicism in large ANs.