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. 2011 Sep 21;286(45):39153–39163. doi: 10.1074/jbc.M111.264697

FIGURE 2.

FIGURE 2.

Gene-dosis dependent up-regulation of CD226. SP thymocytes (A and B) or LN-derived DCs (C and D) of WT (CD155+/+), heterozygous (CD155+/−), and CD155-deficient mice (CD155−/−) were stained to detect expression of CD226 or CD155, respectively. A, representative CD226 stains of SP thymocytes. Light shaded area, isotype control; dark shaded area, WT; dashed line, CD155+/−; solid line, CD155−/−. B, quantitative determination of CD226 levels in SP thymocytes. C, representative CD155 stains of LN resident DCs (CD11c+MHCIIint) and recently immigrated semi-mature DCs (CD11c+MHCIIhi). Light shaded area, CD155−/−; dark shaded area, CD155+/−; solid line, WT. D, quantitative determination of CD155 levels in LN-derived DCs as indicated. Each dot represents cells from one animal of indicated origin. WT, +/+; CD155+/−, +/−; CD155−/−: −/−; **, p < 0.01; ***, p < 0.001.