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. 2011 Sep 9;286(45):39387–39402. doi: 10.1074/jbc.M111.279893

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 3. — Time course study of mitochondrial oxidative stress and mitochondrial pathology after indomethacin treatment. A, time course study of indomethacin-induced oxidation of mitochondrial proteins as measured by protein carbonyl formation. B, time course study of indomethacin-induced mitochondrial lipid peroxidation as measured by thiobarbituric acid-reactive substance (TBARS) formation. C, time course study of mitochondrial transmembrane potential as measured by JC-1 uptake (590/530 nm fluorescence ratio). Detailed descriptions are given under “Experimental Procedures.” Data are presented as mean ± S.E. (***, p < 0.001 versus control; **, p < 0.01 versus control; *, p < 0.05 versus control; n = 6).