TABLE 1.

Occurrence of SelK/SelS-like proteins in eukaryotes

The first two columns show sequenced eukaryotic organisms and the number of predicted proteins that were retrieved from NCBI, respectively. The third column shows proteins that pass the criteria presented in Fig. 2B. Proteins that were found in multiple organisms were considered as members of the SelK/SelS family (shown in the fourth, fifth, and sixth columns).

Organism	Total proteins	Initial candidates	SelK/SelS family		Romo1 subfamily
			Known SelK and SelS proteins	SelK/SelS-like proteins
D. melanogaster	17,878	68	SelK, SelK (Cys)	5	1
C. reinhardtii	15,256	113	SelK
P. falciparum	5,363	49	SelK, SelS	2
C. merolae	5,014	20
L. major	8,280	27	SelK	4
C. elegans	25,811	172	SelK (Cys), SelS (Cys)	10	1
S. cerevisiae	10,814	79		6
H. sapiens	38,806	261	SelK, SelS	33	1
T. nigroviridis	27,918	204	SelK, SelS	16	1
T. rubripes	26,721	151	SelK, SelS	12	1
T. pseudonana	11,397	85		6
Total	193,258	1,229	14	94	5