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. 2011 Oct 21;286(50):43486–43494. doi: 10.1074/jbc.M111.293597

FIGURE 6.

FIGURE 6.

Sensitization of A549 cancer cells to mafosfamide toxicity with ALDH inhibitors. Human lung adenocarcinoma A549 cells were treated with ALDH inhibitors (Aldi-1 and Aldi-3 at 40 μm and Aldi-2 at 25 μm) in the presence or absence of 125 μm mafosfamide (MFM). Cell viability was determined using MTT assays. DMSO, which was used as a solvent for the inhibitors, was used for the control treatment (*, p < 0.0001 ∼ p < 0.0007; n = 8–16).