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Palmitate suppresses cellular bioenergetics and mitochondrial function. a, cellular ATP levels. b, cellular oxygen consumption and mitochondrial potential as measured by the ratio of tetramethylrhodamine ethyl ester perchlorate to MitoTracker green intensities. c, two blots from two separate experiments showing the effect of palmitate on COX-IV subunit 1 (encoded by the mitochondria) and COX-IV subunit 4 (encoded by the nucleus).
