Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Oct 21;286(49):42435–42445. doi: 10.1074/jbc.M110.212845

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 6. — PI(4,5)P₂ and PI(3,4,5)P₃ differentially regulate apoptosis. LLC-PK1 cells were maintained on permeable supports, and pre-treated by incorporation of metabolically stable diC₈-PI(4,5)P₂ or diC₈-PI(3,4,5)P₃. Cells were then induced to undergo apoptosis with staurosporine (STS, 1 μm, 5 h, in panel A) or cisplatin (25 μm, 18 h, 37 °C, in panel B). Apoptosis was quantified by TUNEL. Note the difference in y-axis scale between histograms. *, p < 0.05 compared with staurosporine-only or cisplatin-only groups by analysis of variance.