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. 2011 Oct 13;286(49):42635–42646. doi: 10.1074/jbc.M111.289058

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 8. — AMI cause pain-related behaviors through activation of ASIC3 channels. A, pain-related behaviors as determined by the time spent for following saline or AMI (300 μm or 1 mm or 3 mm) injection (10 μl) in asic3^+/+ and asic3^−/− mice. Data are means ± S.E. n = 6–9. **, p < 0.001 versus saline; ##, p < 0.001, asic3^+/+ versus asic3^−/−. B, pain-related behaviors as determined by the time spent for following saline or AMI (3 mm) injection (10 μl) in asic1^+/+ and asic1^−/− mice. Data are means ± S.E. n = 10. *, p < 0.05, asic1^+/+ versus asic1^−/−.