Table 3.

Regression coefficients and their significance in multiple regression models of mouse expression data

Predictors	Expression level		Expression breadth		Ratio of coefficients (95% CI)a
	Coefficient	Significance	Coefficient	Significance
Gene compactness variables
5′-UTR	−0.07	<10−5	−0.03	NS	2.29 (1.16, 4.54)*
5′-UTR (quadratic term)	0.03	NS	0.03	NS	—
3′-UTR	0.02	NS	0.05	0.002	0.49 (0.20, 1.20)
3′-UTR (quadratic term)	−0.08	<10−6	−0.06	<10−4	1.31 (0.97, 1.77)
Exon size	−0.14	<10−20	−0.08	<10−7	1.75 (1.34, 2.08)*
Intron length	−0.11	<10−11	−0.06	<10−3	1.97 (1.36, 2.84)*
Codon usage bias variable
CAI	0.15	<10−8	0.06	NS	2.45 (1.35, 4.46)*
G+C content variables
GC3	−0.10	<10−3	−0.06	NS	1.78 (0.93, 3.42)
GCp	−0.05	NS	−0.09	<10−6	0.55 (0.34, 0.88)*
GCi	−0.00	NS	0.10	<10−4	—
DNA methylation-related variables
CpGO/E promoter	0.20	<10−24	0.29	<10−51	0.68 (0.61, 0.77)*
CpGO/E intron	0.03	NS	0.00	NS	—
Evolutionary rate variables
dN	−0.21	<10−34	−0.17	<10−24	1.19 (1.06, 1.33)*
dS	0.02	NS	−0.01	NS	—
R2 (adjusted R2)		0.14 (0.13)		0.14 (0.14)

^aEstimated for variables that are significant for at least one expression trait and not zero.

*Ratios significantly different from 1.