Figure 1.

Real time monitoring of TTA-induced growth inhibition of SW620 cells. SW620 colon cancer cells were seeded in 16 well E-plates. After ~24 h, TTA (75 μM) or NaOH (control) were added. Cell growth was monitored using the xCELLigence RTCA DP Instrument (Roche). (A) SW620 cell growth presented as baseline cell index from one representative experiment. (B) Average baseline cell index (± SD) of TTA-treated cells, presented as percent of control, at indicated time points. Mean was calculated from at least two duplicate measurements in four independent experiments. * Significantly different from control (one-tailed Student's t-test, P < 0.05).