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. Author manuscript; available in PMC: 2011 Dec 9.
Published in final edited form as: Pediatr Res. 2008 Jun;63(6):697–701. doi: 10.1203/PDR.0b013e31816fee45

Table 1.

Pyridinium crosslink analysis

Dependent variable Individuals with NF1 with skeletal dysplasia
Individuals with NF1 without skeletal dysplasia
Individuals without NF1
p
LS mean SE N LS mean SE N LS mean SE N
Pyd (umol/mol creatinine) 232.6 16.4 17 220.9 8.3 42 208.3 8.1 99 NS
Dpd (umol/mol creatinine) 71.0 4.2 17 58.9 2.1 42 46.8 2.1 99 <0.001
Dpd/Pyd ratio 0.31 0.009 17 0.27 0.005 42 0.23 0.005 99 <0.001

Comparison of urinary pyridinoline (Pyd) and deoxypyridinoline (Dpd) between individuals with neurofibromatosis type 1 (NF1) with skeletal dysplasia, individuals with NF1 without skeletal dysplasia, and individuals without NF1. p-values generated via multivariate linear regression controlling for age.

LS, least squares; SE, standard error; NS, not significant.