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. Author manuscript; available in PMC: 2011 Dec 9.
Published in final edited form as: J Am Chem Soc. 2009 Sep 2;131(34):12056–12057. doi: 10.1021/ja904441a

Table 2.

“Memory Effect” Observed with Linear Electrophilesa

graphic file with name nihms136602t2.jpg
entry substrate ligand solvent 7:8b yield (%)c ee (%)d
1 5 L1 dioxane >19:1 74 89
2 6 L1 dioxane 1:1.6 71 7:64
8:17
3 5 L2 PhH >19:1 32 3.6
4 6 L2 PhH <1:19 64 63
a

Reactions run under the standard conditions.

b

Determined by 1H NMR of the crude reaction mixture.

c

Combined isolated yield of both regioisomers.

d

Determined by chiral HPLC.