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. 2011 Dec 9;6(12):e28837. doi: 10.1371/journal.pone.0028837

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Lu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. Control A: PC3 luciferase shRNA; Control B: PC3 PLKO vector; SIM2 C: SIM2 sh48; SIM2 D: SIM2 sh51. Gene expressions were either up or down greater than 2 fold in the SIM2^low were listed. B. Top dysregulated signaling pathways in SIM2^low PC3 cells. C. Top dysregulated cell functions in SIM2^low PC3 cells.