Figure 1. Effective deletion of the Lrp1 gene in macrophages from macLRP1-/- mice.

a) Bone marrow derived macrophages from LRP1+/+ and macLRP1-/- mice were analyzed for LRP1 expression by immunoblot analysis. b) Resident macrophages were isolated by peritoneal lavage and incubated with fluorescent labeled RAP for 1 h at 37 ^oC. RAP-positive, F4/80 positive cells were then determined by FACS analysis.