Skip to main content
. 2011 Dec 9;6(12):e28712. doi: 10.1371/journal.pone.0028712

Figure 10. Retinoic acid in the presence of DMSO further increases FPR1 promoter-mediated transcription.

Figure 10

A. Cells were co-transfected with pGL3 Basic-FPR1 −149/41 and pRL-TK and incubated for 48 h in the presence of 1% DMSO ± 100 U/ml tumor necrosis factor α (TNFα), 1 µM all-trans retinoic acid (RA), 10 nM 1,25 (OH)2-vitamin D3 (D3), 100 ng/ml lipopolysaccharide (LPS) and 500 U/ml interferon γ (IFNγ). The results are from three experiments ± S.E.M. Unpaired t test, * p-value<0.05. B. Cells were co-transfected with the pGL3 Basic-FPR1 −149/41 plasmid and pRL-TK and incubated for 48 h in the presence of 1% DMSO ± various concentrations of all-trans retinoic acid (as shown). The graphs show the mean ratios from four experiments ± S.E.M. Unpaired t test, * p-value<0.05.