Table 2. Relationship between peak CSF neurodegeneration biomarker levels and hemorrhage severity.

Grade	CCSctf	NFHsmi35	14-3-3β	14-3-3ζ	UCH-L1	CCSntf	NSE	S100β
2–3	0.5 +/- 0.2	12.9 +/- 11.4	7.7 +/- 4.5	5.3 +/- 1.2	2.8 +/- 1.9	8.6 +/- 2.0	2.3 +/- 1.2	21 +/- 11
4–5	1.7 +/- 0.4	17.1 +/- 12.8	13.8 +/- 5.3	16.5 +/- 6.0	7.0 +/- 2.4	33.1 +/- 16.7	13.1 +/- 4.4	39 +/- 14
P value	0.03	0.81	0.39	0.09	0.21	0.17	0.04	0.35

The mean (+/- S.E.M.) peak level of each biomarker from 3–10 days post-rupture is depicted in relation to the initial severity of the aneurysm dichotomized according to the Hunt-Hess grade.