Table 4. Relationship between early CSF neurodegeneration biomarker increases and the severity of cerebral vasospasm.

Vasospasm	CCSctf	NFHsmi35	14-3-3β	14-3-3ζ	UCH-L1	CCSntf	NSE	S100β
No/Mild	1.6 +/- 0.5	4.7 +/- 2.5	1.3 +/- 0.4	2.6 +/- 0.6	2.0 +/- 0.6	3.2 +/- 0.9	1.1 +/- 0.3	50 +/- 22
Mod/Severe	10.7 +/- 8.4	3.7 +/- 0.8	20.6 +/- 9.7	17.3 +/- 12.7	12.9 +/- 8.9	17.9 +/- 6.9	14.7 +/- 6.8	350 +/- 285
P value	0.22	0.77	0.04	0.19	0.17	0.03	0.04	0.24

The mean (+/- S.E.M.) peak level of each biomarker within 3 days of aneurysm rupture is depicted in relation to dichotomized severity of angiographic vasospasm.