Table 5. Relationship between peak CSF neurodegeneration biomarker levels and outcome at hospital discharge.
Outcome | CCSctf | NFHsmi35 | 14-3-3β | 14-3-3ζ | UCH-L1 | CCSntf | NSE | S100β |
Dead, Nursing | 2.3 +/- 0.6 | 27.1 +/- 22.1 | 20.9 +/- 7.7 | 24.7 +/- 8.4 | 9.8 +/- 3.5 | 53.8 +/- 25.5 | 21.3 +/- 4.0 | 54 +/- 22 |
Rehab/Home | 0.7 +/- 0.2 | 10.9 +/- 8.8 | 6.9 +/- 3.5 | 4.8 +/- 1.0 | 2.4 +/- 1.5 | 7.9 +/- 1.6 | 2.1 +/- 0.9 | 22 +/- 9 |
P value | 0.005 | 0.42 | 0.08 | 0.004 | 0.04 | 0.02 | 0.0001 | 0.13 |
The mean (+/- S.E.M.) peak level of each biomarker from 3–10 days post-rupture is depicted in relation to dichotomized discharge outcome.