Table 6. Relationship between peak CSF neurodegeneration biomarker levels and long-term outcome.

Outcome	CCSctf	NFHsmi35	14-3-3β	14-3-3ζ	UCH-L1	CCSntf	NSE	S100β
GOSE 5-8	0.6 +/- 0.2	17.8 +/- 15.8	9.4 +/- 6.3	4.6 +/- 2.1	3.6 +/- 2.7	9.0 +/- 2.5	2.9 +/- 1.6	27 +/- 15
GOSE 1-4	2.0 +/- 0.5	22.3 +/- 17.8	17.5 +/- 6.8	20.5 +/- 7.7	8.2 +/- 3.2	44.3 +/- 21.9	17.3 +/- 5.0	127 +/- 59
P value	0.04	0.86	0.41	0.08	0.29	0.15	0.03	0.14

The mean (+/- S.E.M.) peak level of each biomarker from 3–10 days post-rupture is depicted in relation to long-term outcome dichotomized according to the Glasgow Outcome Scale - Extended.