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. 2011 Dec 9;6(12):e28915. doi: 10.1371/journal.pone.0028915

Figure 4. Rosiglitazone inhibited TGF-β1-induced collagen type I and fibronectin protein and mRNA synthesis in ADPKD cyst-lining epithelial cells in a concentration-dependent fashion.

Figure 4

Cells were pretreated with rosiglitazone for 1 h, and then incubated with TGF-β1 for 24 h. A. collagen type I and fibronectin protein in TGF-β1-stimulated ADPKD cyst-lining epithelial cells treated with rosiglitazone. B. collagen type I and fibronectin mRNA in TGF-β1-stimulated ADPKD cyst-lining epithelial cells treated with rosiglitazone. All results were representative of three independent experiments with similar results. *P<0.05 vs. control; #P<0.05 vs. TGF-β1.