Figure 6. Evaluation of inhibitory effect of rosiglitazone on TGF-β1 induced Smad2 (A), ERK1/2 (B) and p38MAPK(C) activation in ADPKD cyst-lining epithelial cells.

Cells were pretreated with rosiglitazone for 1 h, and then incubated with rosiglitazone in the presence or absence of TGF-β1 (5 ng/mL) for another 1h. * P<0.05 vs. TGF-β1 alone.