Figure 2.

Expression of detoxification gene families across gossypol dose-tissue experimental conditions. Transcriptional responses of cytochrome P450 s, esterases, UDP-glycosyltransferases and glutathione transferases in gut and the rest of the body are displayed for two gossypol concentrations (CT: 0%; T5: 0.016%; T7: 0.16%). Responses are expressed relative to the median intensity of all data (blue = down-regulation; black = no change; red = up-regulation). Genes were found to be differentially expressed in H. armigera rest of body (RB) larval tissue to a 0.16% (T7) gossypol in the diet relative to the control samples (Welch's t-test, B&H FDR P < 0.001).