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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Child Dev. 2011 Sep 2;84(1):58–75. doi: 10.1111/j.1467-8624.2011.01641.x

Figure 5. Representative example of a gene of potential functional interest associated in girls with paternal stress during preschool uncovered by focused examination of the medium-confidence CpG (cytosine-guanine dinucleotide) site set.

Figure 5

Three CpG sites in the imprinted GNAS locus were negatively associated in girls with paternal stress at preschool. Specifically, these were cg24975842 (rho = − .38, −5.2% DNA methylation change, slope = −.07 (95% CI = −.14 – −.01), FDR = 9.1%), cg21988465 (rho = − .37, −5.9% DNA methylation change, slope = −.08 (95% CI = −.15 – −.02), FDR = 11.7%) and cg07284407 (rho = − .36, −7.5% DNA methylation change, slope = −.11 (95% CI = −.11 – −.02), FDR = 11.7%). No statistically significant association was found in the full group or boys-only analysis The average beta scale was restricted to show values between 0 – 0.5 (A) or 0.3–0.8 (B) rather than the full range of 0–1.0. Girls are represented as triangles with the regression line being wide-dashed.