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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Wiley Interdiscip Rev RNA. 2011 Aug 22;3(1):62–72. doi: 10.1002/wrna.104

Figure 4.

Figure 4

The J1/2 element modulates nanosecond dynamics of the P1 duplex in the open complex of the Tetrahymena group I ribozyme. Simulations of the measured spectra indicate that lengthening J1/2 (from 0, 3, to 8 adenosines) results in decreases in motional ordering (lower order parameter S) and slower rotational diffusion rate (smaller R). This reveals changes in intrinsic dynamics of the P1 duplex upon alteration of J1/2. Figure adopted from Ref. 50 with permission.