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. Author manuscript; available in PMC: 2013 Mar 5.
Published in final edited form as: Mol Pharm. 2011 Sep 21;9(3):374–381. doi: 10.1021/mp2003219

Table 1.

Molar relaxivity, half-life and rate of clearance measured for dendrimers and antibody-dendrimer agents.

Agent r1(mM-1s-1) Half-life (min) Rate of clearance (min-1)
Magnevist™ 4.1 ± 0.5 --- ---
G4SS30 16.4 ± 1.2 12.5 ± 3 0.080 ± 0.025
G5SS58 27.3 ± 1.4 16.3 ± 4 0.061 ± 0.020
Ab-(G4S15)4 6.7 ± 1.1 17.5 ± 3 0.057 ± 0.007
Ab-(G5S29)4 9.1 ± 1.3 22.2 ± 7 0.045 ± 0.011