Table 3.
Bone mineral density and bone mineral content of the total body, total hip and lumbar vertebrae L2–L4 (number of observations in brackets)
| Total (mean ± SD) | Type I (mean ± SD) | Type III (mean ± SD) | Type IV (mean ± SD) | P value | |
|---|---|---|---|---|---|
| Bone mineral density and massa, total body | |||||
| Number of patients | 90 | 68 | 9 | 11 | |
| BMC total body, kg | 2.26 ± 0.66 | 2.40 ± 0.50 | 0.99 ± 0.32 | 2.38 ± 0.50 | <0.001 |
| BMD total body, g/cm² | 1.10 ± 0.11 | 1.11 ± 0.09 | 0.93 ± 0.09 | 1.14 ± 0.10 | <0.001 |
| Z, BMD total body | −0.39 ± 1.03 | −0.29 ± 1.02 | −1.31 ± 0.92 | −0.45 ± 0.89 | 0.02 |
| Bone mineral density and mass (L2–L4) and total hip without pathology | |||||
| BMC L2–L4, g | 37.28 ± 8.86 (52) | 37.60 ± 8.78 (47) | –c | 34.27 ± 10.07 (5) | 0.43 |
| BMC total hip, g | 27.47 ± 7.69 (68)b | 26.97 ± 7.68 (61) | –c | 30.20 ± 8.74 (6) | 0.90 |
| BMD L2–L4, g/cm² | 0.93 ± 0.14 (52) | 0.95 ± 0.14 (47) | –c | 0.82 ± 0.12 (5) | 0.05 |
| BMD total hip, g/cm² | 0.85 ± 0.17 (68)b | 0.84 ± 0.16 (61) | –c | 0.89 ± 0.22 (6) | 0.51 |
| Z, BMD L2–L4 | −1.99 ± 1.09 (52) | −1.87 ± 1.06 (47) | –c | −3.19 ± 0.66 (5) | 0.01 |
| Z, BMD total hip | −1.15 ± 1.22 (68)b | −1.55 ± 1.28 (61) | –c | −1.12 ± 1.77 (6) | 0.32 |
aSeven participants were not investigated with DXA
bTwo were unclassified
cAll patients with OI type III had considerable deformities in both spine and hip and could not be analyzed