FIG. 6.

Nissl staining of brain sections at day 28 post-SAH in the SAH animals treated with phosphate-buffered saline (Vehicle), or 135 mg/kg minocycline (Mino). Damaged neurons exhibited shrunken and dark appearance. Less neuronal loss is seen in the minocycline group in the hippocampus (B, b), cortex (D, d), and diencephalon (F, f ), compared to the vehicle group hippocampus (A, a), cortex (C, c), and diencephalon (E, e). Scale bars represent 400 μm in the hippocampus, and 200 μm in the cortex and diencephalon under low magnification in all panels. Under high magnification scale bars represent 30 μm in all panels (SAH, subarachnoid hemorrhage).