Skip to main content
. 2011 Dec 3;35(2):94–103. doi: 10.1007/s12639-011-0084-x

Fig. 1.

Fig. 1

Falcipains and vivapains have unique features. Falcipains and vivapains are papain family cysteine proteases. The active site residues (Cys, His, Asn) are conserved within papain family. Falcipains and vivapains have unique N-terminus extension act as a refolding domain and C terminus insert as a hemoglobin (Hb) binding domain. The prodomains of falcipains and vivapains have ERFNIN and GNFD motifs, conserved in papain, cathepsin K and cathepsin L