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Structure of Pro-falcipain-2: Purple color showing the mature domain of falcipain-2, solved by X-ray crystallography (Pandey et al. 2009; Wang et al. 2006). The mature domain has active site (catalytic triad residues in orange), hemoglobin binding domain, and refolding domain are labeled. The prodomain (cyan) runs up the face of the mature enzyme before forming helices containing the conserved ERFNIN and GNFD motifs (yellow). (Color figure online)
