Table 4.
Repartition per class of potential drug target proteins, considering those which are central and those considered to be more influential.
| Functional class | Proteins | Drug targets | Central targets | Influential targets | |
|---|---|---|---|---|---|
| 1 | Virulence, detoxification, adaptation | 176 | 31 | 2 | 1 |
| 2 | Lipid metabolism | 230 | 75 | 35 | 28 |
| 3 | Information pathways | 245 | 85 | 21 | — |
| 4 | Cell wall and cell processes | 618 | 112 | 52 | 5 |
| 5 | Insertion seqs and phages | 82 | 10 | — | — |
| 6 | PE/PPE | 147 | 69 | 2 | — |
| 7 | Intermediary metabolism and respiration | 884 | 262 | 93 | 70 |
| 8 | Unknown | 1637 | 169 | 24 | 10 |
| 9 | Regulatory proteins | 176 | 68 | 12 | — |
|
| |||||
| Total | 4195 | 881 | 241 | 114 | |