Table 5.
Comparison of laboratory and clinical data of truly poor mobilizers (defined as not achieving ≥2 × 106 CD34+ cells/kg with first mobilization) during their 1st and 2nd mobilizations.
| 1st mobilization (G-CSF alone) | 2nd mobilization (G-CSF + Plerixafor) | |
|---|---|---|
| Median number of apheresis days (range) | 3 (2–5) | 2 (1–5) |
|
| ||
| Median CD34+ ×106/kg collected (range) | 0.77 (0.24–1.98) | 2.89 (0.72–22.5)* |
|
| ||
| Median WBC on 1st day of apheresis, ×103/mm3 (range) | 30.6 (5–59.6) | 52.8 (21.2–94.6)* |
|
| ||
| Median PLT count on 1st day of apheresis, ×103/mm3 (range) | 114 (39–365) | 132 (44–265) |
†The number of poor mobilizers was 13, 4 multiple myeloma (MM) and 9 lymphoma patients. One MM patient died before transplant, and two patients had tandem transplants. Median transplant cell dose for these patients was 3.68 × 106 CD34+/kg (range, 1.92–5.01).
*Significantly different with P ≤ 0.025.