Table 3.

Group Comparisons of GM and WM for Cortical Parcelled Regions

GM		Control Mean ± SE	Influenza Mean ± SE	p Uncorrected	p ICV-Corrected
Region	Hemisphere
Prefrontal	left	2,815 ± 18	2,619 ± 64	≤.05a
	right	2,884 ± 19	2,680 ± 64	≤.05a
Frontal	left	3,011 ± 42	2,828 ± 72	≤.07
	right	3,027 ± 14	2,812 ± 67	≤.05a	≤.07
Cingulate	left	908 ± 30	808 ± 18	≤.01a	≤.01a
	right	876 ± 33	783 ± 18	≤.01a	≤.01a
Insula	left	342 ± 12	335 ± 7
	right	349 ± 15	327 ± 6	≤.05a
Parietal	left	3,196 ± 30	2,910 ± 71	≤.01a	≤.05a
	right	3,296 ± 20	2,953 ± 71	≤.01a	≤.01a
Temporal Auditory	left	2,042 ± 93	1,923 ± 40	≤.05a
	right	2,022 ± 89	1,880 ± 39	≤.05a
Temporal Visual	left	2,881 ± 31	2,766 ± 73
	right	2,874 ± 21	2,756 ± 67
Temporal Limbic	left	1,124 ± 37	1,073 ± 20	≤.07
	right	1,147 ± 42	1,102 ± 22
Occipital	left	4,078 ± 27	3,932 ± 97
	right	4,066 ± 36	3,927 ± 10

WM		Control Mean ± SE	Influenza Mean ± SE	p Uncorrected	p ICV-Corrected
Region	Hemisphere
Prefrontal	left	812 ± 29	755 ± 18	≤.07
	right	820 ± 36	767 ± 19
Frontal	left	1,451 ± 71	1,375 ± 31
	right	1,430 ± 59	1,387 ± 30
Cingulate	left	149 ± 4	158 ± 6		≤.05a
	right	135 ± 5	143 ± 5a
Insula	left	NC	NC
	right	NC	NC
Parietal	left	1,794 ± 68	1,637 ± 48	≤.05a	≤.05a
	right	1,809 ± 63	1,674 ± 42	≤.05a
Temporal Auditory	left	440 ± 11	409 ± 13	≤.05a
	right	442 ± 9	411 ± 14
Temporal Visual	left	1,387 ± 60	1,339 ± 33
	right	1,380 ± 55	1,340 ± 33
Temporal Limbic	left	153 ± 5	143 ± 6
	right	179 ± 8	172 ± 7
Occipital	left	1,326 ± 48	1,261 ± 34
	right	1,385 ± 54	1,336 ± 34

Significant group differences are shown with and without correcting for ICV (brain region divided by ICV). Data are presented as raw means (mm³) ± SE. Measurement reliability was too low to quantify the small amount of insula WM and was therefore not calculated (NC). Control n = 7, Influenza n = 12.

Abbreviations as in Table 2.

^ap values below .05.