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. 2011 Dec 4;2012:913426. doi: 10.1155/2012/913426

Table 3.

Risks for childhood asthma in relation to delivery modes and birth conditions.

Controls Ever asthma Early-onset asthma Late-onset asthma
N (%)§ N § OR 95%CI N OR 95%CI N § OR 95%CI
Modes of delivery
Vaginal 255 (66.2) 128 1.00 61 1.00 67 1.00
Scheduled CS 58(15.1) 25 1.04 (0.59, 1.83) 13 1.19 (0.49, 2.88) 12 0.97 (0.45, 2.09)
Emergent CS 72(18.7) 38 1.13 (0.70, 1.83) 16 0.76 (0.37, 1.57) 22 1.63 (0.81, 3.28)
Forceps usage during vaginal delivery
 No 250(98.0) 118 1.00 59 1.00 59 1.00
 Yes 5(2.0) 9 2.12 (0.57, 7.91) 2 0.41 (0.04, 3.95) 7 5.10 (0.84, 30.93)
Vacuum usage during vaginal delivery
 No 243(95.3) 103 1.00 51 1.00 52 1.00
 Yes 12(4.7) 24 3.68 (1.34, 10.1)* 10 2.01 (0.47, 8.63) 14 5.16 (1.29, 20.60)*
Low birth weight
 No 338(90.4) 158 1.00 78 1.00 80 1.00
 Yes 36(9.6) 31 1.73 (0.96, 3.1) 13 1.99 (0.77, 5.13) 18 1.76 (0.81, 3.8)
 2000–2500 gm 25(6.7) 22 1.70 (0.86, 3.35) 9 1.61 (0.56, 4.62) 13 1.60 (0.72, 3.55)
 < 2000 gm 11(2.9) 9 1.79 (0.66, 4.87) 4 4.18 (0.65, 26.77) 5 5.69 (0.49, 65.67)
P for trend 0.08 0.10 0.09
Preterm delivery
 No 356(92.2) 169 1.00 80 1.00 89 1.00
 Yes 30(7.8) 24 1.83 (0.98, 3.41) 11 2.47 (0.94, 6.50) 13 1.4 (0.63, 3.27)
 34–36 wk 22(7.2) 16 1.74 (0.81, 3.74) 8 2.51 (0.82, 7.72) 8 1.16 (0.40, 3.36)
 < 34 wk 2(0.7) 5 4.31 (0.81, 2.88) 3 4.80 (0.44, 52.14) 2 4.48 (0.39, 51.97)
P for trend 0.03 0.04 0.32

Models are adjusted for parental education, mother's age at birth of her child, parental history of asthma, parental history of atopy, and in utero maternal smoking.

*P < 0.05.

§Number of subjects does not add up to total n because of missing data.

Early onset: asthma diagnosed ≦3 yr of age.

Late onset: asthma diagnosed >3 yr of age.

Preterm delivery was defined as children born at gestational age less than 37 weeks.